The extracellular matrix is an important structure in maintenance of tissue organisation and in the suppression of cellular proliferation and migration. Excess destruction of the extracellular matrix ...
Background Tendinopathy commonly occurs in tendons with large in vivo loading demands like the Achilles tendon (AT) and supraspinatus tendon (SST). In addition to differences in their local anatomic ...
Introduction The incidence of tendinopathy increases with aging. Alterations to the balance between matrix metalloproteinases (MMPs) and the tissue inhibitors of metalloproteinases (TIMPs) may play a ...
Phase I Study of Topotecan Plus Cranial Radiation for Glioblastoma Multiforme: Results of Radiation Therapy Oncology Group Trial 9507 PURPOSE: A disruption in the balance between the matrix ...
PURPOSE: Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are important in tumor development and progression. MMP expression has been correlated with advanced clinical stage and ...