The brains of mammals continuously combine signals originating from different regions to produce various sensations, emotions ...

The localized loss of sensation with resultant reduction in pain stimuli is the end result of local anesthesia. This mode of anesthesia is considered to be safer than general anesthesia, because it ...

(A) Schematic diagram of the experimental system that detects calcium release from the endoplasmic reticulum by each ryanodine receptor. (B) Isoflurane selectively activates RyR1 (mean ± standard ...

Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations. However, the mechanism of their ...

An impressive new study, led by scientists from the Boston Children's Hospital, has developed a novel method to tame one of the world's most potent toxins, tetrodotoxin, commonly found in the ...

CAMBRIDGE, MA -- Nitrous oxide, commonly known as "laughing gas," has been used in anesthesiology practice since the 1800s, but the way it works to create altered states is not well understood. In a ...

Mechanical embolectomy performed with general instead of local anesthesia is associated with worse clinical outcomes and poorer survival, according to an article published online March 25, 2014, ahead ...

The new approach involve studying the mechanism of anesthetics from the anatomical to the molecular level to sort out the "why" and develop a way to remove pain and allow for live-saving treatments as ...

General anesthetics induce a coma-like state within seconds, allowing patients to be operated on without feeling pain or discomfort. Yet very little is known about how these drugs work. Now research ...