Video: Amines to Amides: Acylation of Amines
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Video: Amines to Amides: Acylation of Amines
2.8K Views. Various carboxylic acid derivatives (such as acid chlorides, esters, and anhydrides) can be used for the acylation of amines to yield amides. The reaction requires two equivalents of amines. The first amine molecule functions as a nucleophile and attacks the carbonyl carbon to produce a tetrahedral intermediate. This is followed by ...
Mar 3, 2023
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